Description
Dosage Forms & Strengths
tablet
500mg
1 g IV/IM; additional doses at q8hr until PO; not to exceed 3 g/day
Total parenteral dose SHOULD NOT EXCEED 3 g/day for >3 days, unless treating tetanus; if condition persists, may repeat therapy after drug-free interval of 48 hr
1500 mg PO q6hr for 48-72 hours; not to exceed 8 g/day THEN decrease to 4-4.5 g/day divided q4-8hr
Tetanus
Adjunct therapy: Initial 1-2 g IV injection (at 300 mg/min), THEN
Additional 1-2 g IV infusion for total dose of 3 g initially
May repeat 1-2 g IV q6hr until can give NG or PO
Total of 24 g PO may be needed
Dosing Modifications
Renal failure: Not studied; parenteral dosage form contraindicated due to presence of polyethylene glycol
Hepatic failure: Not studied
Reviews
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